I have been running the optimised apps for mb for as long as I can remember, easy enough to follow those instructions for 32 bit. I have just built a rig with an i7 920 running @ 3.8Ghz and 12Gb of ram and 2 9800 GX2's and Vista ultimate 64bit. I would like some help with instrucion on what I need to do to run the optimised apps of mb and ap 5.03 with the 64 bit client. Also ,is it possible to run the optimised apps concurrently with CUDA apps? Are there any optimised CUDA apps yet? Lot's of questions I know, but I am enthusiastic and fairly good with instructions so, any help would be greatly appreciated